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- Open Access
Evaluation of reducing temporal resolution on the accuracy of aortic pulse wave velocity assessment from velocity encoded MRI
© Sala et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Pulse Wave Velocity
- Aortic Stiffness
- Aortic Pulse Wave Velocity
- Repeated Scanning
- Data Removal
Five patients referred for cardiac MRI and ten healthy volunteers within similar age range (mean age 32 ± 14 years) were prospectively included. PWV was assessed from velocity mapping using VE MRI on 3T MRI (Ingenia, Philips) with velocity sensitivity of 150 cm/s. Reference PWV (PWVref) was achieved from VE MRI with maximal number of reconstructed phases (Tres = 5 ms). The effect of temporal Tres on PWV was evaluated by temporal downsampling (50% [Tres = 10 ms], 67% [Tres = 15 ms], 75% [Tres = 20 ms], and 80% [Tres = 25 ms]), first by reducing phases during repeated reconstruction of the original acquired high-temporal data. Next, downsampling was performed by data removal as well as by data averaging from the reference PWV data set. Finally, this was compared to PWV from repeated scanning with decreasing Tres to evaluate the effect of physiologic variation in combination with temporal downsampling. Relative unsigned differences (RUDs) with respect to PWVref were calculated for downsampled data.
Physiological changes introduce up to 7% variation in PWV. When allowing less than 7% error in PWV assessment, Tres of at least 20 ms is required. Reducing Tres in retrospective ECG-gated VE MRI does not correspond with data removal or averaging of high-temporal VE MRI data.
Part of this research was funded by an unconditional grant provided by Dr. Rainer Bluemm.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.