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Coronary artery bifurcation haemodynamics - comparison between phase contrast MRI and computational fluid dynamics
© Beier et al.; licensee BioMed Central Ltd. 2014
Published: 16 January 2014
Coronary atherosclerosis is common at vessel bifurcations. A quantitative approach to measuring blood velocity, vorticity and more complex flow features at bifurcations would enhance the understanding of the mechanisms of atheroma development, and potentially predict vessels at highest risk. The aim of this work was to validate 4D phase contrast (PC) magnetic resonance imaging flow measurements using a simplified arterial model of the left main coronary bifurcation against computational fluid dynamic (CFD) modelling.
The standard deviation of the differences between the PC and CFD data was less than 10%. Regional flow features such as vortices were identified in the PC data, and were found to be subjectively similar to the corresponding features in the CFD data. Regions of PC artefact were identified using the CFD results, and were associated with lower spatial resolution and background eddy current effects.
PC MR flow measurements show good quantitative and structural flow similarity to CFD. CFD may be useful for the identification of regions of artefact in PC data and potentially provide a means of correction or regularisation.
Auckland Heart Group Charitable Trust.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.