- Poster presentation
- Open Access
Radial cardiac T2 mapping with alternating T2 preparation intrinsically introduces motion correction
© Feliciano et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Source Image
- Bloch Equation
- Healthy Adult Volunteer
- Heart Rate Variation
- Signal Readout
A navigator-gated ECG-triggered radial gradient-recalled-echo pulse sequence (20 lines per heartbeat, trigger every 3 heartbeats) was implemented to obtain source images for the T2 maps (van Heeswijk et al., JACCCardiovImag2012), with the possibility to apply the T2Prep durations of 60/30/0 ms in both an alternating and sequential manner. Bloch equation simulations were performed in order to estimate the fitting residual due to T1 relaxation (van Heeswijk et al., JACCCardiovImag2012) as well as the accuracy over a range of heart rates. The sequences were validated at 3T (12-channel surface coil array, on a Magnetom Trio, Siemens, Erlangen, Germany) in agar-NiCl2 phantoms by comparing the resulting T2 maps to gold-standard spin-echo (SE) T2 measurements. A mid-ventricular short-axis T2 map was then acquired with both pulse sequences in 7 healthy adult volunteers. The myocardial surface area was measured in the T2 maps, while a Student's t-test was applied to detect differences in T2 values and surface area.
We successfully implemented and tested a T2 mapping methodology in which magnetization preparation is alternated. The in vivo T2 maps demonstrate that the alternated acquisition intrinsically aligns its sources images, resulting in a larger available myocardial surface, which in turn may allow for more accurate T2 value quantification.
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