- Poster presentation
- Open Access
Comparison of breath hold and free breathing respiratory triggered retrospectively cardiac gated cine steady-state free precession (RT-SSFP) imaging in adults
© Wang et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Free Breathing
- Image Quality Score
- Global Left Ventricular Function
- Respiratory Trigger
- SSFP Sequence
The cine steady-state free-precession (SSFP) is the standard sequence for left ventricular (LV) function evaluation. However, SSFP mandates uninterrupted RF excitations to maintain steady-state (SS) during suspended respiration. In patients who cannot perform breath-holds (BH), a respiratory triggered (RT) free breathing (FB) retrospectively cardiac gated cine SSFP sequence that drives the magnetization to SS before commencing cine acquisition may be an alternative . In this work, we validate the RT FB SSFP sequence by comparing it to the BH SSFP sequence for LV function evaluation.
This prospective study included 21 consecutive patients (age range: 23-86 years, 12 male) undergoing clinically indicated CMR. MR Acquisition: Images covering the LV in short-axis (SA) were acquired on a 1.5 T MR scanner (Achieva, Philips Healthcare) using identical parameters for both BH and FB RT cine SSFP sequences - TR/TE/flip angle: 2.6/1.32/70 degrees; acquired voxel size: 1.7-2.0 × 1.6-2.0 × 8 mm3; SENSE acceleration factor: 1.3-1.9; 12-14 slices to cover the LV; temporal resolution: 30 - 40 ms. Data Analyses: Image sets were randomized and anonymized. Two fellowship-trained cardiac imagers blinded to the study design independently scored image quality for myocardium-to-blood pool contrast, endocardial edge definition and inter-slice alignment on a 3-point scale (1-excellent; 2-good; 3-poor). Readers also performed independent quantitative volumetric analyses on both image sets by manually drawing the LV endocardial and epicardial contours.
Bland-Altman analysis of LV volumetric indices for FB and RT techniques for both the readers.
± 1.96 sigma
The FB RT-SSFP sequence generates diagnostic image sets with contrast and spatio-temporal resolution that is comparable to BH SSFP sequence at the expense of a modest time penalty. Given that the LV functional parameters obtained from the two sequences were in good agreement, the FB RT sequence offers a robust alternative method for LV function evaluation in patients with impaired breath-holding capacity.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.