- Poster presentation
- Open Access
Automated registration of dynamic contrast enhanced DCE-MRI cardiac perfusion achieves comparable diagnostic accuracy to manual motion correction: a CE-MARC sub-study
© Zakkaroff et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Myocardial Blood Flow
- Image Registration
- Motion Correction
- Myocardial Perfusion Reserve
- Quantitative Perfusion
The human interaction required for manual motion correction/contouring of cardiac perfusion series remains a significant obstacle to quantitative perfusion gaining a wider acceptance in clinical practice. The use of image registration for motion correction in perfusion data offers a considerable time saving. Numerous registration methods have been proposed, with evaluation limited to the image registration accuracy. However, the important clinical question is how do these methods affect diagnosis? The aim of this study is to evaluate perfusion series registration in terms of its affect on the diagnostic accuracy of myocardial ischaemia.
We have shown that automated motion correction provides diagnostic accuracy equivalent to the common protocol of manual motion correction. Automated motion correction offers a significant time reduction in the human interaction required for delineation of contours for quantitative perfusion analysis, and therefore opens the way for a more widespread use of this technique in research and clinical practice.
This work was funded by the Top Achiever Doctoral scholarship awarded by the Tertiary Education Commission of New Zealand.
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