- Poster presentation
- Open Access
Improved pulse wave velocity wave front detection by template-matching
© Sharkey-Toppen et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Pulse Wave Velocity
- Simple Linear Regression
- Aortic Stiffness
- Perimenopausal Woman
- Atherosclerosis Risk Factor
Pressure waves distributed through the aorta by left ventricular contraction propagate at a rate known as the pulse wave velocity (PWV). PWV is a measure of aortic stiffness, and increased PWV has been correlated with increased coronary artery disease risk. PWV can be measured by velocity-encoded magnetic resonance (PC-MR), with velocity profiles collected at a minimum of two locations along the vessel. The commonly used simple linear regression method computes PWV from detected wavefronts in each profile and distance along the aorta. Recognizing the limitation imposed on wave front detection by simple maximum impulse by noise in the signal producing local maxima, we designed and tested a template-matching scheme to improve PWV estimation.
A template-matching scheme provides more robust estimation of aortic PWV compared to maximum impulse detection. This approach warrants incorporation into longitudinal studies of cardiovascular risk and aortic pathophysiology to improve reliability of PWV as an outcome measure.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.