- Poster presentation
- Open Access
Accelerated self-gated UTE of murine heart
https://doi.org/10.1186/1532-429X-16-S1-P59
© de Graaf et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
Keywords
- Compress Sense
- Mouse Heart
- Compress Sense Reconstruction
- Cine Acquisition
- Radial Acquisition
Background
Sequences with ultra-short echo time (UTE) are popular for their ability to measure tissue components with short T2*. For cardiac applications, UTE MRI was recently employed to detect fibrosis after myocardial infarction [1] and diffuse fibrosis during progression to heart failure [2]. Here we introduce a self-gated UTE MRI sequence for the mouse heart with golden-angle radial acquisition and compressed sensing (CS) reconstruction.
Methods
(a) The self-gated UTE sequence. (b) Comparison between (top) FLASH and (bottom) self-gated UTE reconstruction at (left) end-diastole and (right) end-systole.
Results
Comparison between linear and CS reconstructions for 2-, 4-, and 6X undersampling kt space at end-systole.
Conclusions
6X undersampled UTE Cine acquisition of the mouse heart was achieved with high image quality and without significantly compromising the determination of cardiac functional parameters. Whole heart coverage can be obtained in less than 8 min.
Funding
This research is funded by the Imaging Science & Technology group Eindhoven.
Authors’ Affiliations
References
- de Jong S, et al: J Mol Cell Cardiol. 2011, 1-6.Google Scholar
- Van Nierop, et al: ISMRM. 2013, abstract nr. 1360Google Scholar
Copyright
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.