- Poster presentation
- Open Access
Temporal stability of gel relaxation-time phantoms for quality control of T1 and extracellular volume fraction measurements
© Heng et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Magnetisation Transfer
- Longe Relaxation Time
- Automatic Adjustment
- Volume Fraction Measurement
- Extracellular Volume Fraction
Quantification of interstitial fibrosis by T1-mapping continues to gather momentum clinically with the recognition that extracellular volume fraction (ECV) measurements are pathologically elevated in a range of conditions. Well-known dependence of ECV estimation on imaging parameters requires quality-control by T1 phantoms[1–3]. These typically comprise agarose with NiCl doping, and are often used short-term, but with limited long-term data. Such phantoms might assure long-term stability (over years) of methods applied in patients eg against scanner alterations. We therefore sought to assess their long-term T1 and T2 stability.
Adequate stability of phantoms was shown over 10 weeks to support their continued use in ascertaining long-term precision of T1 mapping.
NIHR Royal Brompton Cardiovascular Biomedical Research Unit and NHLI, Imperial College London.
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