- Poster presentation
- Open Access
3D LGE imaging of the LV short axis stack using spiral readouts at 3T
© Pierce et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Late Gadolinium Enhancement
- Late Gadolinium Enhancement Imaging
- Spiral Acquisition
- Acquisition Duration
- Paired Wilcoxon Sign Rank Test
Clinical assessment of the viability of myocardium is commonly performed using 2D breath-hold late gadolinium enhancement (LGE) imaging with Cartesian k-space coverage and data acquisition windows (AWs) ranging from 140-200 ms. More efficient k-space coverage using spiral trajectories could allow improved spatial resolution and reduced AWs without greatly extending acquisition durations. To this end, we have developed a navigator-gated spiral 3D LGE sequence and present the results in 10 patients attending for clinical 2D LGE imaging on a 3T Siemens Skyra scanner.
The navigator-gated 3D sequence consisted of a stack of spirals (acquired: 8 kz at 1.4 × 1.4 × 10 mm, reconstructed: 16 slices at 0.7 × 0.7 × 5 mm). Each spiral readout was 10 ms long with 16 interleaves required to fill kx-ky space. All 8 kz for a given spiral interleaf were acquired in a single cardiac cycle (AW = 88 ms). Acquisition duration was 34 cardiac cycles assuming 100% respiratory efficiency (alternate R-wave gating). 3D imaging was performed after the acquisition of a stack of conventional clinical breath-hold 2D LGE images in 10 patients (acquired resolution: 1.4 × 1.8 mm reconstructed to 0.7 × 0.7 mm). The 2D images had slice thickness of 7 mm with slice gap of 3 mm. Acquisition duration was 14 cardiac cycles per slice (alternate R-wave gating). LV blood SNR and blood-myocardium CNR in conventional 2D and spiral 3D scans were compared in 3 matched slices (basal, mid and apical) using paired Wilcoxon signed rank test.
Navigator-gated 3D spiral LGE imaging allows contiguous coverage of the LV with higher spatial resolution, shorter acquisition windows and reduced acquisition durations when compared to a stack of conventional breath-hold 2D LGE Cartesian acquisitions.
Wellcome Trust Grant WT093953MA NIHR - National Institute for Health Research.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.