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Accelerating spiral tissue phase velocity mapping without affecting peak velocity measurements
Journal of Cardiovascular Magnetic Resonance volume 16, Article number: W31 (2014)
TPVM is a promising technique for measuring myocardial mechanics  but long scan times have limited its clinical application, despite acceleration techniques such as view-sharing  or k-t BLAST  being used. Cartesian work using k-t BLAST found that accelerations greater than a factor of 2 affected peak velocity measurements, possibly because of temporal smoothing inherent in the technique . Recently spiral trajectories have been shown to be capable of greatly reducing scan duration in comparison with similar resolution Cartesian sequences . A new spiral TPVM sequence which uses the Gadgetron  GPU implementation of non Cartesian SENSE has been developed: this abstract compares peak velocities measured with different acceleration factors.
K-space is fully sampled with 8 spiral interleaves (14 ms duration, TR 24 ms). Data is acquired at 2 levels of acceleration, acquiring 4 (R2) and 3 (R3) out of the 8 spirals in order to assess the effect of acceleration on the measured velocities. Velocity compensated and encoded data are acquired in consecutive heartbeats, with an initial heartbeat used to collect coil sensitivity information (breath-hold durations are 17 and 13 heartbeats for R2 and R3). Acquired spatial resolution is 1.7 × 1.7 mm (reconstructed pixel size 0.85 × 0.85 mm). Retrospective cardiac gating is used to cover the entire cardiac cycle (50 phases reconstructed). Images are passed to the Gadgetron for reconstruction and returned to the scanner for viewing within 1 min 20 s. Basal, mid and apical short-axis slices were acquired in 10 healthy volunteers on a Siemens Skyra 3T scanner.
Example images and velocity maps for R2 and R3 are shown in Figure 1. Very little difference in image quality or measured velocities is seen between levels of acceleration. Figure 2 shows the mean and SD peak velocity values for R2 and R3 in all three slices and all three directions. Velocities measured with R2 and R3 were extremely similar, with no significant differences between measured peaks or TTPs.
The use of spiral trajectories, non-Cartesian SENSE and the Gadgetron GPU reconstruction framework has allowed the acquisition of high temporal resolution TPVM images within a breath-hold time that is easily achievable in the clinical environment (13 heartbeats), while reconstruction time is short enough to allow viewing at the time of scanning. The acceleration is not affecting peak velocity measurements (comparisons with previous unaccelerated spiral data  also suggest this).
NHIR CBRU, Royal Brompton Hospital. HRUK grant RG2584.
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Simpson, R., Keegan, J., Gatehouse, P. et al. Accelerating spiral tissue phase velocity mapping without affecting peak velocity measurements. J Cardiovasc Magn Reson 16 (Suppl 1), W31 (2014). https://doi.org/10.1186/1532-429X-16-S1-W31
- Coil Sensitivity
- Entire Cardiac Cycle
- Spiral Trajectory
- Royal Brompton Hospital
- Phase Velocity Mapping