- Oral presentation
- Open Access
Blood flow pattern in the ascending aorta after TAVI and conventional aortic valve replacement: Analysis using 4D-Flow MRI
© Trauzeddel et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Wall Shear Stress
- Aortic Valve Replacement
- Aortic Diameter
- Orifice Area
- High Surgical Risk
Transarterial aortic valve implantation (TAVI) is a valid alternative to treat aortic stenosis in patients with high surgical risk. The impact of TAVI on changes in blood flow dynamics in the ascending aorta has not been systematically analyzed. Using temporally resolved, three-dimensional, phase contrast MRI (4D-flow), we studied 3D hemodynamics in the ascending aorta (AAo) after TAVI and compared the results to patients with conventional aortic valve replacement (AVR) as well as healthy controls.
We enrolled 17 subjects with TAVI (Edwards Sapien, mean age 77±7 years, 9 males), 12 with biological AVR (77±4 years, 8 males), and 9 healthy subjects (55±16 years, 8 males). All underwent 4D-flow MRI at 1.5T (spatial resolution 1.8 x 1.8 x 2.5mm3, temporal resolution 40.8ms). Analysis included quantification of the regional distribution of peak systolic wall shear stress (WSS) and peak systolic flow velocity in the AAo.
TAVI and AVR lead to similar alterations in systolic blood flow patterns in the ascending aorta compared to healthy controls.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.