- Poster presentation
- Open Access
Comparison of cardiovascular magnetic resonance feature tracking and tagging for the assessment of left ventricular systolic strain in acute myocardial infarction
© Khan et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Cardiovascular Magnetic Resonance
- Late Gadolinium Enhancement
- Transmural Infarction
- Acute STEMI
- Dysfunctional Myocardium
Contractile dysfunction following ST-segment elevation myocardial infarction (STEMI) predicts prognosis. CMR-measured tagging is the gold standard technique for myocardial strain assessment. Strain offers greater accuracy in detecting dysfunctional myocardium than ejection fraction and visual measures of regional function. Tagging however requires acquisition of additional sequences and time-consuming post-processing. FT tracks features of interest along contour lines on routinely acquired steady-state free-precession (SSFP) cine images. There are no published strain data using FT in acute STEMI. This study aimed to assess the feasibility of FT measured global and segmental circumferential (Ecc) and longitudinal (Ell) strain assessment post acute STEMI and compare values to those obtained with tagging.
CMR at 1.5T was performed in 24 acute STEMI patients. SSFP, T2wSTIR (oedema) and Late Gadolinium Enhancement (infarct) imaging were performed in long-axis views and contiguous short-axis slices covering the left ventricle. Pre-contrast short and long-axis tagged images were acquired using a spatial modulation of magnetization gradient-echo sequence. Segmental infarct and oedema were calculated as a percentage of segmental area. Global and segmental Ecc and Ell were assessed using FT (Tomtec Image Arena, Germany) and tagging (InTag, France). Ecc and Ell on FT and tagging were correlated with total and segmental infarct size and oedema, assessed in relation to segmental transmural infarction, and compared in infarct, adjacent and remote segments. Intraobserver and interobserver variability of the techniques were compared.
Myocardial tracking and quantification time by method
Feature Tracking (FT)
p value (FT v Tagging)
Short-axis cine segments excluded
Long-axis cine segments excluded
Number of excluded short-axis segments in infarct core
Number of excluded long-axis segments in infarct core
Analysis time per patient (minutes)
Post-processing time per patient (minutes)
Total analysis time (minutes)
FT-derived global Ecc and Ell measurement in acute STEMI is feasible and robust. FT-derived strain is quicker to analyse, tracks myocardium better, has better interobserver variability and stronger correlations with infarct and oedema than tagging and more accurately predicts transmural infarction.
National Institute for Health Research (NIHR).
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