Volume 17 Supplement 1

Abstracts of the 18th Annual SCMR Scientific Sessions

Open Access

Adenosine cardiac magnetic resonance: follow-up of patients with very high cardiovascular risk

  • Alberto Esteban-Fernández1,
  • Isabel Coma-Canella1,
  • Gorka Bastarrika-Aleman2,
  • Joaquín Barba-Cosials1,
  • Nahikari Salterain-Gonzalez1 and
  • Pedro M Azcárte-Aguero1, 2
Journal of Cardiovascular Magnetic Resonance201517(Suppl 1):P193

https://doi.org/10.1186/1532-429X-17-S1-P193

Published: 3 February 2015

Background

Stress cardiac magnetic resonance with adenosine (CMR-A) is a valid test to rule out myocardial ischaemia. We follow-up a cohort of patients with CMR-A due to suspected myocardial ischaemia, considering patients with very high cardiovascular risk.

Methods

We included all patients with CMR-A between June 2009 and November 2012, considering two groups: those with a very high cardiovascular risk (prior myocardial infarction or/and Diabetes mellitus) and the rest of the patients. The follow-up was done in outpatient cardiology clinic or by phone. We analyse free-event survival considering: acute coronary syndrome (ACS), death for any cause, admission for heart failure (HF) or necessity of revascularization as endpoints. The statistical analysis was made with SPSS 20.0.

Results

The follow-up of 239 patients (180 male) was done. 134 (56%) were re-classified as high cardiovascular risk patients and 105 (44%) as non-high cardiovascular risk ones. The basal characteristics of each group are summarize in table 1.
Table 1

Characteristics of the patients with CMR-A to rule out myocardial ischaemia considering cardiovascular risk

 

High cardiovascular risk (n=134)

Non-high cardiovascular risk (n=105)

Age-years old

68.0±8.3

63.8±11.8

Diabetes mellitus-no (%)

Basal glucose (mg/dL)

HbA1c (%)

93 (69.4)

125±41

7.0±1.4

-

103±33

6.1±1.3

No tobacco history-no (%)

48 (35.8)

55 (52.4)

Arterial hypertension-no (%)

97 (72.4)

69 (65.7)

Dyslipidaemia-no (%)

104 (77.6)

53 (50.5)

BMI (kg/m2)

29.8±6.1

27.1±4.7

Previous ictus-no (%)

12 (9.0)

4 (3.1)

Peripheral arterial disease-no (%)

33 (24.6)

7 (6.7)

Previous myocardial infarction-no (%)

PCI revascularization-no (%)

CABG revascularization-no (%)

68 (50.7)

51 (38.1)

29 (21.6)

 

Result in CMR-A

Positive-no (%)

Negative-no (%)

-

56 (41.8)

78 (58.2)

-

27 (25.7)

78 (74.3)

Events in follow-up-no (%)

ACS-no (%)

Death for any cause-no (%)

Admission for HF-no (%)

Revascularization-no (%)

51 (38.1)

21 (15.7)

8 (6)

2 (1.5)

20 (14.9)

17 (16%)

5 (4.8)

8 (7.6)

3 (2.9)

1 (1)

CMR-A was positive for myocardial ischaemia in 83 patients (35%) and negative in 156 (65%). The follow-up median was 25 months, with events in 68 patients. The results of the test and the events during the follow-up in each group are attached in table 1.

The analysis of Kaplan-Meier survival curves (1 and 2), considering the cardiovascular risk and the result of the test, showed statistical differences only in very high cardiovascular risk patients (Long Rank test; p=0.024).

Figure 1

Conclusions

In this cohort of patients with very high cardiovascular risk, those with a negative result have fewer events in the follow-up. CMR-A allows a better classification of the global cardiovascular risk

Funding

There is not any funding to support this trial.

Authors’ Affiliations

(1)
Cardiology Department, Clínica Universidad de Navarra
(2)
Radiology Department, Clínica Universidad de Navarra

Copyright

© Esteban-Fernández et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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