- Poster presentation
- Open Access
A realistic MR compatible aortic phantom to validate hemodynamic parameters from MRI data: aortic coarctation patients comparison using catheterization
© Urbina et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Hemodynamic Parameter
- Left Subclavian Artery
- Systolic Pressure Gradient
- Medical Image Technology
- Flexible Silicone
Recently, 3D printing technologies have emerged as a very innovative technique to produce anatomical replicas. Nevertheless, vessel phantoms built up to now are simplified models, with difficulties to obtain parameters with physiological values. The aim of this work is to show and validate a MR compatible thoracic aorta system, designed to obtain hemodynamic parameters within a range comparable to healthy volunteers and patients with aortic coarctation (AoCo).
The phantom is a closed circuit integrated by a MR compatible unit pump with a control unit (Shelley Medical Imaging Technologies) and a realistic aortic model built with flexible silicone (Elastrat). Three non-return valves were installed to avoid negative pressures. Additionally, shut-off valves were added to regulate the flow distribution between the different vessels. We built an 11 mm AoCo, which was placed in the descending aorta just after the left subclavian artery. Additionally, we equipped the system with a catheterization unit to measure invasive pressure along the AoCo.
Phantom data were compared with 3D PC-MRI data acquired in 10 healthy volunteers, and 2 unrepaired aortic coarctation patients. Patient data were acquired in a combined MRI/Catheter interventional suite.
Results in this study demonstrate the feasibility of our realistic aortic system to simulate physiologic and pathologic hemodynamic parameters through an AoCo.
Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT), Ministerio de Educación, Chile. Grant Number: FONDECYT #1141036.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.