- Poster presentation
- Open Access
Whole-heart T1-mapping with single breath-hold
© Chung et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Late Gadolinium Enhancement
- Heart Beat
- Representative Patient
- Short Acquisition Time
- Longitudinal Relaxation Time
T1-mapping, directly measuring the underlying longitudinal relaxation times (T1), and extracellular volume (ECV) quantification, are emerging techniques for myocardial fibrosis quantification. Recent studies have reported significant T1 differences in fibrotic and normal tissue, but whole-heart T1-mapping is rarely performed in clinical practice, due to the associated time-consuming data acquisition; this can lead to sampling error when the fibrotic process is not homogenous. Signal acquisition over multiple heart beats can also be problematic, due to the potential for motion artifacts. In this study, we present a rapid whole-heart T1-mapping in a single breath-hold of, e.g., 6 heartbeats (typically, 5-7 seconds for total 9 T1 maps).
While conventional T1-mapping methods are very time-consuming for routine clinical application, this whole-heart T1-mapping method can be performed well in patients with cardiac disease-related problems, including arrhythmia or difficulty with breath-holding, due to its short acquisition time of, e.g., 6 heartbeats. Better characterizing whole-heart fibrosis may allow for more accurate and earlier diagnosis. Further studies are warranted.
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