Volume 17 Supplement 1
Cervial artery dissection: value of 3D high resolution vessel wall magnetic resonance imaging for diagnosis and follow-up
© Yang et al; licensee BioMed Central Ltd. 2015
Published: 3 February 2015
Cervical artery dissection (CD) is an important cause of stroke in young and middle-aged patients. Sampling perfection with application-optimised contrast using different flip angle evolutions (SPACE) sequence can provide fast 3D isotropic T1 FS images, with very good dark blood contrast. This study aims to demonstrate the value of a 3D fat-saturated SPACE for the diagnosis and follow up of CD.
Twenty-one patients were prospectively evaluated on a 3.0-T MR system for a clinical suspicion of acute or sub-acute cervical artery dissection with 3D T1 SPACE sequence. All scans were performed with the routine head and neck coil. The HR-MRI protocol contained at least three sequences: 3D-TOF, 2D-T1WI and 3D-SPACE. For each patient, coronal, oblique and/or curvilinear multiplanar reconstructions were generated from 3D T1 SPACE datasets. These patients underwent HR-MRI every three months until the double-lumen sign disappeared or until the patients had no appreciable changes for two consecutive times of scanning or turned to operation due to deterioration. The final diagnosis was established in consensus, after reviewing all the imaging and clinical data.
3D SPACE sequence offers similar information with its 2D counterpart, in a shorter acquisition time and larger coverage area. Multiplanar reconstructions were very useful in tortuous regions, such as the atlas loop of the vertebral artery or the carotid petrous entry which was missed by 2D-TSE. MRI would be a reliable mean for the diagnosis and follow-up of CD.
This work has been supported by NSFC 81322022.
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