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Hemodynamic effects of the carotid abnormalities courses by MRI and ultrasound

  • 1,
  • 2,
  • 1,
  • 1 and
  • 1, 3
Journal of Cardiovascular Magnetic Resonance201517 (Suppl 1) :P415

https://doi.org/10.1186/1532-429X-17-S1-P415

  • Published:

Keywords

  • Internal Carotid Artery
  • Cardiac Cycle
  • Blood Flow Velocity
  • Peak Systolic Velocity
  • Arterial Blood Flow

Background

The aim of our investigation was to determine effect of the internal carotid arteries (ICAs) tortuosity (S-shape), kinking and coiling on the arterial blood flow by magnetic resonance imaging and ultrasound (US).

Methods

50 healthy volunteers (control group) and 43 patients with carotid abnormalities (CAs) were examined on 1.5T MR-scanner using routine MR protocol and quantitative MR angiography (qMRA) for estimate of the arterial blood flow velocity and cross sectional area of the ICA. We observed the cross sectional area and the values of peak velocity, mean velocity, flux velocity of arterial blood flow at one cardiac cycle at cervical and intracranial segments of the ICA (Fig. 1). 20 volunteers were performed US for the assessment of the vascular wall and peak systolic velocity (PSV) values of the arterial blood at the portion between common carotid artery (CCA) bifurcation and ICA. Statistical analysis was performed by mean value and confidence interval (for p=0.05). Student's paired t-test was used to indicate significant differences between mean values at the patient and control groups.
Figure 1
Figure 1

Investigated ICA segments in normal course (a) and abnormalities course (b - S-shape, c - coiling, d - kinking): 1 - C1, cervical segment (proximal part); 2 - C1, cervical segment (middle part); 3 - C2, petrous segment (vertical part); 4 - C2, petrous segment (horizontal part); 5 - C5, cavernous segment.

Results

The shapes of the graphs of the mean velocity depending on the phase of the cardiac cycle were the same in the case of the control and CAs groups obtained by MRI and US. The values of blood flow velocity parameters were significant differences at different segments of the ICA in the control and CAs groups (Fig. 2). There were no significant differences between values of the arterial blood velocity parameters in case of the tortuosity (S-shape), kinking and coiling at different segments of ICA. The cross sectional area of the vessel was significantly higher at the all investigated parts in case of CAs (Fig. 2). The correlation coefficient between the values of peak systolic velocity obtained by ultrasound and MRI was low (-0.01)
Figure 2
Figure 2

Cross-sectional area (d) and arterial blood flow velocity parameters (a - flux velocity, b - peak velocity, c - mean velocity) at different ICA segments. * - significant differences between values cross-sectional area and arterial blood flow velocity parameters of the ICA at control groups (n=100) and CAs group (n=67), p=0,05

Conclusions

Type of the artery pulsation at CAs is the same as the control group and corresponds to the musculo-elastic arteries. CAs affects the hemodynamic throughout the artery whith a background of increasing the area of its cross section. The ultrasound has confirmed the results obtained on MRI qualitatively, but correlation coefficient for quantitative parameters was low.

Funding

This work was financially supported by the Russian Science Foundation (project # 14-35-00020).

Authors’ Affiliations

(1)
International Tomography Center SB RAS, Novosibirsk, Russian Federation
(2)
Institute of Physiology and Fundamental Medicine SB RAMS, Novosibirsk, Russian Federation
(3)
Novosibirsk State University, Novosibirsk, Russian Federation

Copyright

© Stankevich et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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