- Poster presentation
- Open Access
Quantification of the area-at-risk by T1 and T2 mapping CMR at 3T
© Bulluck et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Left Ventricle
- Siemens Healthcare
- Manual Segmentation
- STEMI Patient
- Myocardial Salvage
Measuring the area-at-risk (AAR) allows the assessment of myocardial salvage in reperfused STEMI patients. T2-weighted CMR has been used to quantify the AAR but is hampered by low signal-to-noise ratio and image artifacts. T1 and T2 mapping CMR may improve upon this. We compared T1 and T2 mapping for quantifying the AAR at 3T.
T1 and T2 mapping CMR can accurately quantify the AAR at 3T in reperfused STEMI patients. Although both mapping techniques yielded similar results, more work needs to be done to see if T1 mapping has any benefit over T2 mapping in patients with very short onset to balloon time; stability of the signal up to 2 weeks post myocardial infarction and whether therapies reducing edema by T2 mapping also affects T1 mapping.
This work was supported by the British Heart Foundation (FS/10/039/28270;FS/10/72/28568), the Rosetrees Trust, and the National Institute for Health Research University College London Hospitals Biomedical Research Centre.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.