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Positive contrast spiral imaging of a nitinol guidewire
© Campbell-Washburn et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Device Image
- Field Inhomogeneity
- Positive Contrast
- Catheterization Procedure
- Continuous Scanning
The clinical translation of MRI-guided cardiovascular catheterization has been limited by the unavailability of devices that are both visible and safe under MRI. In particular, rigid metallic guidewires are essential for most catheterization procedures and are at risk of heating during MR imaging . Here we present an MRI method that simultaneously improves the visualization of commercially available nitinol guidewires and minimizes RF induced heating.
RF-efficient gradient echo spiral imaging was chosen to minimize heating (8 interleaves, TE/TR = 0.86/10ms, flip angle = 10°). Through-slice dephasing generated a positive contrast "device image" , exploiting local field inhomogeneity such that the metallic guidewire appears hyperintense with background signal suppressed. An anatomical image and a device image were interleaved in alternating frames. Image processing (signal thresholding and selection of elongated structures) was performed on the device image to isolate the guidewire signal from other sources of field inhomogeneity.
Imaging was performed on a 1.5T MRI scanner (Aera, Siemens, Erlangen, Germany). MRI-guided left heart catheterization was performed in a pig using a 0.035" commercially available nitinol guidewire (Nitrex, Covidien, Plymouth, MN). The RF induced temperature rise at the tip of an insulated nitinol rod during MR imaging was measured in the ASTM 2182 gel phantom using a fiberoptic temperature probe (OpSense, Quebec, Canada).
This method simultaneously improves guidewire visualization using a real-time color overlay and minimizes heating using RF-efficient imaging. Thus, this method may permit the safe and effective use of standard commercially available metallic guidewires for MRI-guided cardiovascular catheterizations.
This work was supported by the NHLBI DIR (Z01-HL006039-01, Z01-HL005062-08).
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