- Walking poster presentation
- Open Access
LV rotational mechanics in patients with dilated cardiomyopathy compared to healthy individuals: Experience from the European CMR Registry
© Ochs et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Dilate Cardiomyopathy
- Feature Tracking
- Basal Rotation
- Apical Rotation
- Short Axis Orientation
Left ventricular rotation is an important part of myocardial mechanics during the cardiac cycle. Understanding the mechanisms of LV rotation in different cardiac diseases could play an important role for diagnosis, risk stratification and prediction of heart failure. We sought to analyze LV rotation using the feature tracking technique in patients with dilated cardiomyopathy (DCM) included in the European CMR Registry.
82 Patients diagnosed with DCM and a control group consisting of 30 healthy volunteers were analyzed using dedicated feature tracking imaging software (2D CPA MR©, TomTec Imaging Systems GmbH). An apical, midventricular and basal slice in short axis orientation were tracked to analyze the peak rotation of each slice. LV twist (defined as the difference of peak apical and peak basal rotation at isochronal time points) and LV torsion (defined as the LV twist per ventricular length) were calculated.
Comparison of DCM patients and the control group with normally directed rotation
apical rotation (°)
basal rotation (°)
Direction of rotation: Distribution of DCM patients and the control group
inversed apical rotation
inversed basal rotation
inversed rotation in both layers
DCM is associated with an inverted direction of rotation in a significant amount of cases, predominantly affecting the LV apex. Patients with a normal direction of rotation exhibit significant lower torsion. These findings warrant further investigation including clinical follow-up data in order to analyze their impact on clinical outcome in patients with DCM.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.