- Technologist presentation
- Open Access
Pulmonary arterial pressure: a look into the future
© Williams et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Nitric Oxide
- Pulmonary Arterial Pressure
- Left Pulmonary Artery
- Pulmonary Pressure
Pulmonary Hypertensive (PH) is an incurable , and often fatal disease. Currently a patient's treatment requires periodic office visits to evaluate their progression of right heart failure and increased pulmonary arterial pressures associated with this disease. Invasive and serial right heart catherization (RHC) is the current accepted method for assessing pulmonary arterial pressures and objectively tracking a patient over time. There is an obligate morbidity and mortality associated with serial RHC's. Further, with an estimated >1000 new diagnoses yearly and their requirement for serial RHC's, a novel approach to measuring pulmonary arterial pressures that might have added utility beyond a simple manometer is warranted.
Use of a unique implantable device, CardioMEMs®, recently approved by the FDA (Feb 2014), permits real time evaluation of a patient's pulmonary pressures on a minute-by-minute basis. Novel integration of CMR data with the manometer capacity permits comparison and tracking of pulmonary pressure changes under certain applied stressors.
This CMR and CardioMEMs® showed strong pressure correlation ( 0.91).
A comprehensive evaluation of the RV/PA system is possible using CMR and the implanted CardioMEMs® pressure measuring device. Given the many stressors, it now possible to use CMR in a most efficient manner to obtain heretofore invasively-mandated clinical information in completely non-invasive manner.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.