Feature tracking (FT) and extracelluar volume (ECV) by cardiac magnetic resonance segmentally analyze change of LV in Ebstein:a novel perspective in myocardial remodeling
© Yang et al. 2016
Published: 27 January 2016
Ebstein anomaly is classically considered a malformation of right heart, however, left ventricular is also affected. As LV heart failure is the most common during the natural history, an understanding of heart failure modes is quite significant. Some study have described that the Ebstein's LV basal narrowing, apical modestly dilation, and basal septal dyskinesis but in most ebstein patients the LVEF preserved. The mechanism of the change of LV of Ebstein is not conmon known, but its clinic value draw us searching deeper.
So we sought to assess the segmental change in cardiovascular magnetic resonance (CMR) tissue tracking parameters and segmentally quantify Ebstein's LV degree of myocardial diffuse fibrosis by extracelluar volume fraction (ECV), in turn explore the potential mechanism of the LV change
FT and ECV are sensitive to document segmental change in cardiac function and histopathology. Additionally, FT and ECV together illustrated that diffuse myocardial fibrosis also existed differential distribution in patients, which negatively related to segmental change in cardiac function. This would be a novel perspective in clinically therapy and prognosis assessment.
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