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Table 1 Demographic, echocardiographic and CMR data for patients and controls

From: Myocardial Perfusion Reserve but not fibrosis predicts outcomes in initially asymptomatic patients with moderate to severe aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in AS study- PRIMID AS

  AS Patients (n = 174) Healthy Controls (n = 23) p-value
Age (years) 66.2 ± 13.3 68.3 ± 8.8 0.331
Male (n (%)) 133 (76.4) 16 (69.6) 0.471
Echocardiography data
AV Vmax (m/s) 3.86 ± 0.56 1.35 ± 0.27 <0.001*
AVAI (cm2/m2) 0.57 ± 0.14 1.71 ± 0.36 <0.001*
Lateral E/e' 9.88 ± 3.72 8.07 ± 2.97 0.026*
VAI (Echo) (mmHg/ml/m2) 3.96 ± 1.06 3.67 ± 0.76 0.220
CMR data
LVEDVI (ml/m2) 87.58 ± 18.27 78.16 ± 9.40 <0.001*
LVESVI (ml/m2) 38.28 ± 10.65 32.11 ± 5.03 <0.001*
LVEF (%) 56.7 ± 4.95 58.9 ± 3.67 0.044*
LVMI (g/m2) 57.69 ± 13.85 44.31 ± 7.20 <0.001*
LV mass/volume (g/ml) 0.66 ± 0.11 0.57 ± 0.08 <0.001*
VAI (MRI) (mmHg/ml/m2) 3.81 ± 0.82 3.50 ± 0.74 0.078
Global MPR 2.27 ± 0.70 3.16 ± 0.65 <0.001*
LGE present (n,%) 82 (47.1) 5 (21.7) 0.025*
% LGE (%) 4.20 ± 3.76 2.00 ± 2.21 <0.001*
Native myocardial T1 (ms) 1131.9 ± 69.54 1092.3 ± 34.29 <0.001*
ECV (%) 24.82 ± 2.43 25.05 ± 2.57 0.680
  1. AV Vmax=peak aortic jet velocity, AVAI=aortic valve area indexed to BSA, VAI=valvulo-arterial impedance, LVEDVI=left ventricular end-diastolic volume indexed to BSA, LVESVI=left ventricular end systolic volume indexed to BSA, LVEF=left ventricular ejection fraction, LVMI=left ventricular mass indexed to BSA, MPR=myocardial perfusion reserve, LGE=late gadolinium enhancement, ECV=extracellular volume fraction