- Poster presentation
- Open Access
Improved myocardial T1 mapping for patients with implanted cardiac devices
© Shao et al. 2016
- Published: 27 January 2016
- Late Gadolinium Enhancement
- Implantable Cardioverter Defibrillator
- Image Artifact
- Acquisition Scheme
- Inversion Pulse
Myocardial T1 mapping holds promise for non-invasive evaluation of diffuse fibrosis. Nevertheless, the widely used cardiac T1 mapping techniques, including MOLLI and SASHA, are generally not applicable to patients with implanted cardiac devices, such as implantable cardioverter defibrillators (ICDs) and pacemakers, due to large off-resonance induced by the device and the associated banding artifacts when using bSSFP readouts. We sought to develop and validate an improved technique for accurate myocardial T1 mapping in patients with implanted cardiac devices.
Wideband FLASH-MOLLI was evaluated using 8 phantom studies and validated in 10 healthy volunteers and 5 patients with ICDs using a 1.5T MR scanner. The effects of off-resonance frequency variation, heart rate variation, and presence of ICD on T1 estimation accuracy were investigated using phantom studies. To mimic ICD-induced image artifacts, the ICD generator was attached to the body coil and close to the left shoulder of healthy volunteers. The original FLASH-MOLLI sequence using a 3-(3)-3-(3)-5 acquisition scheme was used to image one healthy volunteer (before and after ICD attachment) and in one patient with ICD for comparison.
This study demonstrates the feasibility of using wideband FLASH-MOLLI for accurate myocardial T1 mapping in patients with implanted cardiac devices through mitigation of image artifacts associated with conventional T1 mapping techniques.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.