- Poster presentation
- Open Access
Breath-held high-resolution cardiac T2 mapping with SKRATCH
© Lugand et al. 2016
- Published: 27 January 2016
- Myocardial Area
- Radial Acquisition
- Cardiac Edema
- Weighted Image Contrast
- Undersampling Artifact
We demonstrated that navigator-gated KWIC-filtered cardiac T2 mapping (Shared K-space RAdial T2 Characterization of the Heart, SKRATCH) enables a considerable decrease in acquisition time while maintaining the T2 precision . The goal of this study was to extend this approach to a short breath-held high-resolution T2 map acquisition and to compare its performance to navigator-gated T2 mapping.
The novel breath-held SKRATCH protocol consisted of a GRE sequence with a continuously increasing golden-angle radial acquisition. This ensured a unique k-space trajectory for all 64 lines of each of the 4 T2Prep durations (0/30/45/60 ms), pixel size of 1.2 × 1.2 × 8 mm3 and a total duration of 7 heartbeats. As reference, a navigator-gated radial cardiac T2 mapping GRE sequence was acquired with 3 T2Prep durations (0/30/60 ms), 308 lines/image and a pixel size of 1.25 × 1.25 × 5 mm3 . Images were acquired at 3T (Magnetom Prisma, Siemens Healthcare) in 17 healthy volunteers at the same midventricular short-axis orientation with both protocols. The T2 maps were segmented according to the AHA guidelines . The mean T2 value (μT2) and the relative standard deviation (σR = standard deviation/ μT2) of each segment as well as the myocardial area were calculated and tested for significant differences. The SKRATCH T2 map was acquired twice in 11 of the volunteers for Bland-Altman reproducibility analysis.
The SKRATCH T2 maps were highly similar to the reference high-resolution T2 maps, while the shortening to breath-hold duration came at the cost of an acceptably small increase in standard deviation and decrease in myocardial area. These encouraging results will need to be validated in future high-resolution studies in patients.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.