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- Open Access
Longitudinal strain correlated with haemodynamics in patients with chronic thromboembolic pulmonary hypertension
© Liu et al. 2016
- Published: 27 January 2016
- Heart Rate
- Cardiac Output
- Pulmonary Hypertension
- Vascular Resistance
to determine the feasibility of the longitudinal strain assessed by Trufistrain on four-chamber images of Cardiac MRI in patients with chronic thromboembolic pulmonary hypertension and to correlate with right heart catheterization.
After informed consent, 36 patients (age, 45.9 ± 10.1 years; male/female= 25/11, Heart rate=65 ± 8bpm) with chronic thromboembolic pulmonary hypertension (CTEPH) underwent CMRI at 3T (TimTrio, Siemens) and right heart catheterization in the same day. After Four-chamber cine images were acquired during short breath-holds with a retrospectively gated turbo FLASH gradient-echo sequence and the longitudinal strain independently measured by two radiologists on four-chamber cine images with Trufistrain (Siemens). The hemodynamics was evaluated with right heart catheterization. The feasibility of the longitudinal strain assessed by Trufistrain. The feasibility of strain evaluated with Trufistrain were assessed with A Bland-Altman plot and correlation of strain with hemodynamics was evaluated with Spearman correlation on Medicalc and SPSS
In this work, we demonstrated the feasibility of the longitudinal strain measurement on Cine images by Trufistrain. And the longitudinal strain correlated with PAP, CO and PVR. These suggest longitudinal strain measurement on Cine images by Trufistrain is promising to assess hemodynamics. In the future, we will analyze the correlation of longitudinal strain with myocardial function and fibrosis.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.