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Table 1 Segmental ventricular wall thickness, stress and function in hypertrophic cardiomyopathy and normal subjects

From: Lower-than-normal myocardial stress and excess hypertrophy from CMR are associated with worsening ventricular contractile performance in hypertrophic cardiomyopathy

 

Normal subjects (144 segments)

HCM Group 2 (261 segments)

HCM Group 1 (43 segments)

ANOVA p value

End-diastolic wall thickness (mm)

6.16 ± 1.36

9.31 ± 2.53#

19.10 ± 3.55#*

<0.001

Wall stress (WS) (× 1000 N/m2)

13.30 ± 5.70

7.46 ± 3.80#

4.23 ± 1.10#*

<0.001

Regional EF (%)

70 ± 10

67 ± 15

64 ± 12

NS

Area strain (AS) (%)

74 ± 18

68 ± 26#

49 ± 12#*

<0.001

Stress-corrected area strain (Sc-AS) (%)

100 ± 20

70 ± 23#

38 ± 10#*

<0.001

  1. # HCM Group 2 and HCM Group 1 vs normal subjects; * HCM Group 1 vs HCM Group 2