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Accelerated phase contrast measurements of fetal blood flow using compressed sensing
Journal of Cardiovascular Magnetic Resonance volume 18, Article number: P30 (2016)
Phase contrast (PC) MR is routinely used to quantify blood flow in postnatal subjects and through the use of metric optimized gating (MOG) has been employed in studies of fetal blood flow in both normal pregnancies and fetal congenital heart disease [1–3]. Still, the scan time required for high resolution fetal PCMR remains a practical limitation. Recently, compressed sensing (CS) has been integrated with MOG for accelerated CINE imaging of the fetal cardiac anatomy . Here we examine the feasibility of CS for reconstructing retrospectively undersampled PC MR measurements of fetal vessels.
Fully sampled PCMR data from the ascending and descending aorta were acquired in five fetal subjects (2 normal, 3 congenital heart disease). Typical fetal scan parameters where: VENC 150 cm/s, field of view 240 × 240 mm2, voxel size 1.25 × 1.25 × 5 mm3, TR/TE 6.6 ms/2.92 ms, 4 views per segment, scan time ~34 seconds. For each fully sampled data set MOG was performed to create time resolved CINE data sets which were then retrospectively undersampled (R = 2,4,6) and quantitatively compared to the fully sampled MOG data.
Figure 1 shows an example flow curve of the human fetal ascending aorta for both fully sampled and undersampled (R=6) reconstructions. Figure 2 demonstrated comparable measurements of total blood volume per cardiac cycle between fully sampled and undersampled reconstructions (R=6). Finally a Bland-Altman plot (Figure 2b) shows good agreement between the two reconstruction methods.
The feasibility of CS for reconstructing accelerated PC MR measurements of human fetal blood flow was accessed through retrospective undersampling of fully sampled MOG data. The results yielded accurate flow measurements for acceleration rates up to R=6. Further study using prospectively undersampled data is needed to evaluate this technique for clinical use.
Jansz , et al: Magn. Reson. Med. 2010, 64: P31-
Prsa : Circ Cardiovas Imaging. 2014, 7 (4): 663-
Al Nafisi : J Cardiovas Magn Reson. 2013, 15: 65-
Roy , et al: Proc. 23rd ISMRM. 2015, 3689-
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Roy, C., Seed, M. & Macgowan, C. Accelerated phase contrast measurements of fetal blood flow using compressed sensing. J Cardiovasc Magn Reson 18, P30 (2016). https://doi.org/10.1186/1532-429X-18-S1-P30
- Congenital Heart Disease
- Compress Sense
- Total Blood Volume
- Cardiac Anatomy
- Contrast Measurement