- Poster presentation
- Open Access
Serial assessment of left atrial deformation in patients undergoing pulmonary vein isolation: a cardiovascular magnetic resonance feasibility study
© Bergau et al. 2016
- Published: 27 January 2016
- Cardiovascular Magnetic Resonance
- Left Atrial
- Pulmonary Vein Isolation
- Left Atrial Function
- Stable Sinus Rhythm
Left atrial (LA) performance quantification using Cardiovascular Magnetic Resonance (CMR) is of growing interest. There is evidence that declined left atrial function is associated with a poorer outcome following pulmonary vein isolation (PVI) in atrial fibrillation (AF). Furthermore, the influence of PVI on left atrial performance has not yet been investigated comprehensively. This study was designed to investigate the feasibility of CMR using comprehensive myocardial feature tracking (CMR-FT) and volumetric analyses for serial investigation of atrial performance before and after PVI.
Eight consecutive patients (age 59 ± 11 years, 50 % male, 38 % persistent AF) undergoing PVI was included. All patients received manually guided PVI using open-irrigated radiofrequency ablation catheters. All patients underwent CMR (either 1.5 or 3T) ahead of PVI and 3 months afterwards. LA longitudinal strain and strain rate (SR) parameters as well as fractionated LA-volume changes were derived from long-axis 2- and 4-chamber cine images using dedicated software (2D CPA MR, TomTec, Germany and QMass Version 7.6, Medis Medical Systems, The Netherlands). LA performance was assessed calculating LA reservoir function (total strain [εs], peak positive SR [SRs]), LA conduit function (passive strain [εe], peak early negative SR [SRe]) and LA booster pump function (active strain [εa], late peak negative SR [SRa]).
Serial assessments of atrial phasic performance using CMR is feasible before and after PVI. Future studies will need to relate changes in these novel quantitative parameters to atrial fibrosis and outcome to define their incremental clinical merit.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.