- Poster presentation
- Open Access
Ferumoxytole-enhanced 4D MR angiography with retrospectively defined temporal resolution
© Zhou et al. 2016
- Published: 27 January 2016
- Cardiac Phase
- Control Mechanical Ventilation
- Subjective Image Quality
- Image Quality Score
- High Spatial Resolution Image
In cardiovascular MRI applications, high spatial resolution is preferable for anatomical evaluation of vascular structures and high temporal resolution is desired in cardiac functional assessment. As a result, current CMR protocol usually includes repeated scans of the same anatomy with different resolution settings. To address this issue, we propose a technique that allows for retrospective trade-off between temporal and spatial resolution based on a single image acquisition. The proposed technique is applied on Ferumoxytol-enhanced 4D angiography application so that images with high temporal and high spatial resolution are available from separated reconstructions.
9 clinical indicated pediatric patients with congenital heart disease were included in this study. General anesthesia was performed with controlled mechanical ventilation. Scan was performed on a Siemens 3.0T scanner with the following parameters: TE/TR = 0.9/2.9 ms, FA = 25, FOV = 500 × 300 × 150 mm3, 0.8-1 mm isotropic resolution without interpolation, TA~6 min. In this study, each dataset was binned using two settings: 6 cardiac phases@80 ms and 18 phases@25 ms. Image reconstruction was performed in our CPU and GPU accelerated inline image reconstruction system.
The proposed ROCK sampling pattern and data binning strategy enables retrospectively defined temporal resolution. Our initial results suggest that simultaneous anatomical and functional assessment is possible based on two separate reconstructions of a single 4D scan, although further validation on subjective image quality scores and quantitative LV functional measurements is warranted.
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