Left atrial wall imaging using a novel black-blood late gadolinium enhancement sequence
© Tang et al. 2016
Published: 27 January 2016
Seven patients (6 male, 65+/-17 years) with a history of atrial fibrillation were recruited to participate in an IRB-approved study to compare BB-LGE vs. LGE for imaging of the atrial wall. All images were acquired at 1.5T (Philips Achieva). LGE and BB-LGE scans were acquired 15-20 minutes after injection of 0.1 mmol/kg of MultiHance contrast agent. Both sequences were acquired with identical imaging parameters and spatial resolution; BB-LGE required an additional T2-prep to null the blood signal. The parameters of the BB-LGE sequence (Δt1, Δt2, Δt3 in Fig. 1) were determined in a short ~30 sec navigator scan by a technologist prior to the BB-LGE scan. Images were subjectively scored by an observer according to percentage of the LA border that was clearly defined. A score of 1 was given for scans in which greater than 75% of the border was well-defined. A score of 2 was given for 50-75%, a score of 3 was given for 25-50%, and a score of 4 was given for less than 25% of the LA border. The scores for each sequence were compared using a paired T-test analysis.
Our proposed BB-LGE sequence has the potential to provide improved visualization of the LA wall compared to LGE protocols due to its ability to simultaneously null both the healthy myocardium and blood pool signals. This preliminary data demonstrates the need for further study of this sequence in patients with suspected LA fibrosis.
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