- Workshop presentation
- Open Access
A T1 and ECV phantom for global T1 mapping quality assurance: The T1 mapping and ECV standardisation in CMR (T1MES) program
© Captur et al. 2016
- Published: 27 January 2016
- Dielectric Permittivity
- Gold Standard Measurement
- Local Calibration
- Lower Temperature Sensitivity5
- PMMA Bead
Myocardial T1 and extracellular volume (ECV) estimates have applications in a range of myocardial diseases. Factors responsible for systematic inaccuracies in T1 mapping are beginning to be known1-4 but little is known about its delivery at ‘health-care system' scale and there is no global quality assurance (QA) system. Agarose phantoms are common in MRI and nickel ions preferred for lower temperature sensitivity5. This program aims to
1 Create a partnership to design 1.5/3T phantoms for any manufacturer/sequence reflecting myocardial/blood T1 pre/post-contrast
2 Test and mass produce phantoms to regulatory standards
3 Distribute globally
4 Analyse serial scans to understand T1 mapping at scale
5 Publish recipes
6 Explore delivery of a ‘T1/ECV Standard' via local calibration
We report results of steps 1-3.
We created a collaboration to develop CE/FDA-approved phantoms for QA of T1 and ECV protocols. 70 revised phantoms with a multi-vendor user manual are now being distributed to centres worldwide for a 1-year academic exploration of T1 mapping sequences, platform performance and stability.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.