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Table 1 Bias and regional agreement in paired IR and PSIR LGE images from multi-center patient studies

From: A new automatic algorithm for quantification of myocardial infarction imaged by late gadolinium enhancement cardiovascular magnetic resonance: experimental validation and comparison to expert delineations in multi-center, multi-vendor patient data

  Magnitude IR LGE Phase sensitive IR LGE PSIR vs IR
Bias to expert delineation [%LVM] R-value DSC full extent DSC core extent Bias to expert delineation [%LVM] R-value DSC full extent DSC core extent Bias [%LVM] R-value
EWA algorithm 0 ± 5 0.89 0.82 ± 0.14 0.81 ± 0.15 −1 ± 5 0.88 0.82 ± 0.17 0.79 ± 0.15 −1 ± 4 0.91
Original weighted algorithm −7 ± 8 0.68 0.70 ± 0.32 0.67 ± 0.32 * * * * * *
EM threshold 6 ± 7 0.88 - 0.67 ± 0.14 6 ± 8 0.86 - 0.68 ± 0.14 0 ± 6 0.91
2SD threshold 7 ± 7 0.85 - 0.69 ± 0.15 8 ± 6 0.86 - 0.70 ± 0.13 1 ± 5 0.94
3SD threshold 0 ± 7 0.81 - 0.70 ± 0.21 −2 ± 7 0.79 - 0.70 ± 0.19 −2 ± 4 0.94
5SD threshold −8 ± 8 0.68 - 0.50 ± 0.33 −13 ± 10 0.38 - 0.36 ± 0.31 −4 ± 6 0.81
FWHM (min) threshold −8 ± 9 0.54 - 0.58 ± 0.20 9 ± 12 0.47 - 0.69 ± 0.17 18 ± 12 0.44
FWHM (remote) threshold ** ** - ** −8 ± 7 0.74 - 0.66 ± 0.19 ** **
Otsu threshold −8 ± 11 0.50 - 0.50 ± 0.32 10 ± 15 0.46 - 0.64 ± 0.20 18 ± 17 0.35
  1. Bias as % of left ventricular mass (%LVM), regression R-value and regional agreement by DSC to expert delineation for the EWA algorithm, the original weighted algorithm [14] and the threshold method of EM, 2SD, 3SD and 5SD from remote, and FWHM from minimum intensity [8], FWHM from mean intensity in remote [12] and Otsu's threshold [26] in paired magnitude inversion recovery (IR) and phase sensitive inversion recovery (PSIR) images (n = 49) and bias and regression R-value for PSIR vs IR LGE images. * the original weighted algorithm by Heiberg et al. [14] was developed for IR images and therefore only applied in IR images. ** the FWHM remote threshold was developed for PSIR images as part of the FACT algorithm by Hsu et al. [12] and therefore only applied in PSIR images