- Poster presentation
- Open Access
Instantaneous Signal Loss simulation (InSiL) - an alternative algorithm for myocardial T1 mapping using the MOLLI sequence
© Shao et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Phantom Study
- Myocardial Scar
- Longitudinal Magnetization
- Phantom Data
- Phantom Result
Myocardial T1 mapping is an emerging technique that is valuable for assessment of diffuse myocardial scar. Currently, the modified Look-Locker inversion-recovery (MOLLI) sequence has been widely used for T1 mapping and it uses 3-parameter exponential fitting with Lock-locker correction for T1 estimation. MOLLI is known to underestimate myocardial T1 values at longer T1s and/or at higher heart-rate. We propose an alternative T1 estimation method, Instantaneous Signal Loss simulation (InSiL), to improve T1 estimation accuracy and reduce the dependency of T1 estimation on heart rate for the MOLLI sequence.
Compared with the standard MOLLI, the proposed InSiL approach can reduce the heart-rate dependence in T1 estimation and achieves better T1 estimation accuracy, without any change in the pulse sequence.
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