- Oral presentation
- Open Access
Phantom validation of 4D flow: independent validation of flow velocity quantification using particle imaging velocimetry
© Töger et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Particle Imaging Velocimetry
- Vortex Ring
- Particle Imaging Velocimetry Measurement
- Phase Contrast Magnetic Resonance
- Particle Imaging Velocimetry Velocity
4D phase contrast magnetic resonance blood flow measurements (4D PC-MR) is a promising tool for clinical assessment of cardiac function, but lack of independent validation may limit clinical adoption. Previous validation studies are limited by lack of pulsatility [1, 2] or by the need of a post hoc correction factor to compensate for differences in experimental setup between 4D PC-MR and reference imaging . Therefore, we aimed to validate 4D PC-MR velocity measurements with particle imaging velocimetry (PIV) as the reference standard in a phantom setup based on vortex ring formation, which has previously shown excellent repeatability .
This study shows that 1) the proposed vortex ring flow phantom can be used for validation of 4D PC-MR measurements, 2) 4D PC-MR shows good overall agreement in velocity for the pixel-wise comparison, but underestimates peak velocities by 8-25% compared to PIV.
This study was supported by Swedish Research Council grants VR 621-2005-3129, VR 621-2008-2949, and VR K2009-65X-14599-07-3, National Visualization Program and Knowledge Foundation grant 2009-0080, the Medical Faculty at Lund University, Sweden, the Region of Scania, Sweden and the Swedish Heart-Lung Foundation.
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