- Oral presentation
- Open Access
Coronary Atherosclerosis T1-weighed Characterization with integrated anatomical reference (CATCH)
© Xie et al. 2016
- Published: 27 January 2016
- Optical Coherence Tomography
- Coronary Plaque
- Optical Coherence Tomography Image
- Anatomical Reference
- Plaque Feature
The detection of high-risk coronary atherosclerotic lesions before severe plaque complications is the "holy grail" in cardiology. Recently T1-weighted (T1w) MRI with  or without  contrast enhancement (CE) has been used for characterizing coronary plaques showing promising prognostic value . However the drawbacks of current protocols based on conventional Cartesian acquisition and navigator gating hinder the clinical application of this technique: a) coverage is limited to proximal coronary segments; b) spatial resolution is low and often anisotropic; c) because normal tissue in T1w images is highly suppressed, a separate MRA acquisition is needed to provide anatomical reference. The purpose of this work is to develop a highly accelerated MR technique for coronary plaque characterization with 1) whole-heart coverage, 2) fine isotropic spatial resolution, and 3) simultaneously acquired bright-blood anatomical reference.
The proposed MR technique of accelerated T1w whole heart coronary plaque characterization with simultaneously acquired anatomical reference was feasible. Coronary plaque hyper-intensity showed positive association with certain high-risk plaque features on OCT.
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