Articles
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Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:88
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Atlas-based analysis of 4D flow CMR: Automated vessel segmentation and flow quantification
Flow volume quantification in the great thoracic vessels is used in the assessment of several cardiovascular diseases. Clinically, it is often based on semi-automatic segmentation of a vessel throughout the ca...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:87 -
Real-time aortic pulse wave velocity measurement during exercise stress testing
Pulse wave velocity (PWV), a measure of arterial stiffness, has been demonstrated to be an independent predictor of adverse cardiovascular outcomes. This can be derived non-invasively using cardiovascular magn...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:86 -
Validation of high temporal resolution spiral phase velocity mapping of temporal patterns of left and right coronary artery blood flow against Doppler guidewire
Temporal patterns of coronary blood flow velocity can provide important information on disease state and are currently assessed invasively using a Doppler guidewire. A non-invasive alternative would be benefic...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:85 -
Saturation pulse design for quantitative myocardial T1 mapping
Quantitative saturation-recovery based T1 mapping sequences are less sensitive to systematic errors than the Modified Look-Locker Inversion recovery (MOLLI) technique but require high performance saturation pulse...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:84 -
The effect of high-permittivity pads on specific absorption rate in radiofrequency-shimmed dual-transmit cardiovascular magnetic resonance at 3T
Dual-channel transmit technology improves the image quality in cardiovascular magnetic resonance (CMR) at 3 T by reducing the degree of radiofrequency (RF) shading over the heart by using RF shimming. Further ...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:82 -
Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide
Cardiovascular Magnetic Resonance (CMR) has become a primary tool for non-invasive assessment of cardiovascular anatomy, pathology and function. Existing contrast agents have been utilised for the identificati...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:83 -
Non-invasive determination by cardiovascular magnetic resonance of right ventricular-vascular coupling in children and adolescents with pulmonary hypertension
Pediatric pulmonary hypertension (PH) remains a disease with high morbidity and mortality in children. Understanding ventricular-vascular coupling, a measure of how well matched the ventricular and vascular fu...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:81 -
Fractal frontiers in cardiovascular magnetic resonance: towards clinical implementation
Many of the structures and parameters that are detected, measured and reported in cardiovascular magnetic resonance (CMR) have at least some properties that are fractal, meaning complex and self-similar at dif...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:80 -
Pulmonary artery to aorta ratio for the detection of pulmonary hypertension: cardiovascular magnetic resonance and invasive hemodynamics in heart failure with preserved ejection fraction
Previous work indicates that dilatation of the pulmonary artery (PA) itself or in relation to the ascending aorta (PA:Ao ratio) predicts pulmonary hypertension (PH). Whether these results also apply for heart ...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:79 -
Cardiovascular magnetic resonance predictors of clinical outcome in patients with suspected acute myocarditis
The natural history of acute myocarditis (AM) remains highly variable and predictors of outcome are largely unknown. The objectives were to determine the potential value of various cardiovascular magnetic reso...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:78 -
Systolic ShMOLLI myocardial T1-mapping for improved robustness to partial-volume effects and applications in tachyarrhythmias
T1-mapping using the Shortened Modified Look-Locker Inversion Recovery (ShMOLLI) technique enables non-invasive assessment of important myocardial tissue characteristics. However, tachyarrhythmia may cause mis...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:77 -
Increased myocardial extracellular volume in active idiopathic systemic capillary leak syndrome
The Systemic Capillary Leak Syndrome (SCLS) is a rare disorder of unknown etiology presenting as recurrent episodes of shock and peripheral edema due to leakage of fluid into soft tissues. Insights into SCLS p...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:76 -
Left ventricular mechanical dysfunction in diet-induced obese mice is exacerbated during inotropic stress: a cine DENSE cardiovascular magnetic resonance study
Obesity is a risk factor for cardiovascular disease. There is evidence of impaired left ventricular (LV) function associated with obesity, which may relate to cardiovascular mortality, but some studies have re...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:75 -
Extracellular volume quantification in isolated hypertension - changes at the detectable limits?
Diffuse myocardial fibrosis (DMF) is important in cardiovascular disease, however until recently could only be assessed by invasive biopsy. We hypothesised that DMF measured by T1 mapping is elevated in isolat...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:74 -
T1 mapping and T2 mapping at 3T for quantifying the area-at-risk in reperfused STEMI patients
Whether T1-mapping cardiovascular magnetic resonance (CMR) can accurately quantify the area-at-risk (AAR) as delineated by T2 mapping and assess myocardial salvage at 3T in reperfused ST-segment elevation myoc...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:73 -
4D flow cardiovascular magnetic resonance consensus statement
Pulsatile blood flow through the cavities of the heart and great vessels is time-varying and multidirectional. Access to all regions, phases and directions of cardiovascular flows has formerly been limited. Fo...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:72 -
Cardiovascular magnetic resonance phase contrast imaging
Cardiovascular magnetic resonance (CMR) phase contrast imaging has undergone a wide range of changes with the development and availability of improved calibration procedures, vi...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:71 -
Two repetition time saturation transfer (TwiST) with spill-over correction to measure creatine kinase reaction rates in human hearts
Phosphorus saturation transfer (ST) magnetic resonance spectroscopy can measure the rate of ATP generated from phosphocreatine (PCr) via creatine kinase (CK) in the human heart. Recently, the triple-repetition...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:70 -
Fast assessment of long axis strain with standard cardiovascular magnetic resonance: a validation study of a novel parameter with reference values
Assessment of longitudinal function with cardiovascular magnetic resonance (CMR) is limited to measurement of systolic excursion of the mitral annulus (MAPSE) or elaborate strain imaging modalities. The aim of...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:69 -
Influence of phase correction of late gadolinium enhancement images on scar signal quantification in patients with ischemic and non-ischemic cardiomyopathy
Myocardial fibrosis imaging using late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) has been validated as a quantitative predictive marker for response to medical, surgical, and device therapy...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:66 -
A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
A comprehensive review is undertaken of the methods available for 3D whole-heart first-pass perfusion (FPP) and their application to date, with particular focus on possible acceleration techniques. Following a...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:68 -
Cardiac T2-mapping using a fast gradient echo spin echo sequence - first in vitro and in vivo experience
The aim of this study was the evaluation of a fast Gradient Spin Echo Technique (GraSE) for cardiac T2-mapping, combining a robust estimation of T2 relaxation times with short acquisition times. The sequence w...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:67 -
Estimation of aortic pulse wave transit time in cardiovascular magnetic resonance using complex wavelet cross-spectrum analysis
Aortic pulse wave velocity (PWV), which substantially increases with arterial stiffness and aging, is a major predictor of cardiovascular mortality. It is commonly estimated using applanation tonometry at caro...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:65 -
Abnormal septal convexity into the left ventricle occurs in subclinical hypertrophic cardiomyopathy
Sarcomeric gene mutations cause hypertrophic cardiomyopathy (HCM). In gene mutation carriers without left ventricular (LV) hypertrophy (G + LVH-), subclinical imaging biomarkers are recognized as predictors of...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:64 -
Quantification of LV function and mass by cardiovascular magnetic resonance: multi-center variability and consensus contours
High reproducibility of LV mass and volume measurement from cine cardiovascular magnetic resonance (CMR) has been shown within single centers. However, the extent to which contours may vary from center to cent...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:63 -
Assessment of cardiovascular physiology using dobutamine stress cardiovascular magnetic resonance reveals impaired contractile reserve in patients with cirrhotic cardiomyopathy
Liver cirrhosis has been shown to affect cardiac performance. However cardiac dysfunction may only be revealed under stress conditions. The value of non-invasive stress tests in diagnosing cirrhotic cardiomyop...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:61 -
Left ventricular global function index assessed by cardiovascular magnetic resonance for the prediction of cardiovascular events in ST-elevation myocardial infarction
The left ventricular performance index (LVGFI) as a comprehensive marker of cardiac performance integrates LV structure with global function within one index. In a prospective cohort study of healthy individua...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:62 -
Magnetic susceptibility anisotropy of myocardium imaged by cardiovascular magnetic resonance reflects the anisotropy of myocardial filament α-helix polypeptide bonds
A key component of evaluating myocardial tissue function is the assessment of myofiber organization and structure. Studies suggest that striated muscle fibers are magnetically anisotropic, which, if measurable...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:60 -
Individual component analysis of the multi-parametric cardiovascular magnetic resonance protocol in the CE-MARC trial
The CE-MARC study assessed the diagnostic performance investigated the use of cardiovascular magnetic resonance (CMR) in patients with suspected coronary artery disease (CAD). The study used a multi-parametric...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:59 -
2015 Update on Acute Adverse Reactions to Gadolinium based Contrast Agents in Cardiovascular MR. Large Multi-National and Multi-Ethnical Population Experience With 37788 Patients From the EuroCMR Registry
Specifically we aim to demonstrate that the results of our earlier safety data hold true in this much larger multi-national and multi-ethnical population.
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:58 -
Prediction of response to cardiac resynchronization therapy using left ventricular pacing lead position and cardiovascular magnetic resonance derived wall motion patterns: a prospective cohort study
Despite marked benefits in many heart failure patients, a considerable proportion of patients treated with cardiac resynchronization therapy (CRT) fail to respond appropriately. Recently, a “U-shaped” (type II) w...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:57 -
Myocardial perfusion is impaired in asymptomatic renal and liver transplant recipients: a cardiovascular magnetic resonance study
Myocardial ischemia is a major cause of death in chronic kidney disease (CKD) patients, which can be caused by either epicardial or microvascular coronary artery disease (CAD). Although renal transplantation i...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:56 -
Single centre experience of the application of self navigated 3D whole heart cardiovascular magnetic resonance for the assessment of cardiac anatomy in congenital heart disease
For free-breathing cardiovascular magnetic resonance (CMR), the self-navigation technique recently emerged, which is expected to deliver high-quality data with a high success rate. The purpose of this study wa...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:55 -
The diagnostic value of iron oxide nanoparticles for imaging of myocardial inflammation – quo vadis?
Cardiovascular magnetic resonance (CMR) is an integral part in the diagnostic work-up of cardiac inflammatory diseases. In this context, superparamagnetic iron oxide-based contrast agents can provide additiona...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:54 -
Positive contrast high-resolution 3D-cine imaging of the cardiovascular system in small animals using a UTE sequence and iron nanoparticles at 4.7, 7 and 9.4 T
To show that 3D sequences with ultra-short echo times (UTEs) can generate a positive contrast whatever the magnetic field (4.7, 7 or 9.4 T) and whatever Ultra Small Particles of Iron Oxide (USPIO) concentratio...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:53 -
Left atrial structure and functional quantitation using cardiovascular magnetic resonance and multimodality tissue tracking: validation and reproducibility assessment
Left atrium (LA) strain, volume and function are important markers of cardiovascular disease and myocardial impairment. We aimed to assess the accuracy of LA biplane volume and function measured by Multimodali...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:52 -
Cardiovascular magnetic resonance compatible physical model of the left ventricle for multi-modality characterization of wall motion and hemodynamics
The development of clinically applicable fluid-structure interaction (FSI) models of the left heart is inherently challenging when using in vivo cardiovascular magnetic resonance (CMR) data for validation, due to...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:51 -
Clinical experience of strain imaging using DENSE for detecting infarcted cardiac segments
We hypothesised that myocardial deformation determined with magnetic resonance imaging (MRI) will detect myocardial scar.
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:50 -
Prognostic value of pulmonary vein size in prediction of atrial fibrillation recurrence after pulmonary vein isolation: a cardiovascular magnetic resonance study
The relationship between pulmonary vein (PV) anatomy and successful catheter ablation of atrial fibrillation (AF) is poorly understood
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:49 -
Compressed sensing to accelerate magnetic resonance spectroscopic imaging: evaluation and application to 23Na-imaging of mouse hearts
Magnetic Resonance Spectroscopic Imaging (MRSI) has wide applicability for non-invasive biochemical assessment in clinical and pre-clinical applications but suffers from long scan times. Compressed sensing (CS...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:45 -
Impact of motion correction on reproducibility and spatial variability of quantitative myocardial T2 mapping
To evaluate and quantify the impact of a novel image-based motion correction technique in myocardial T2 mapping in terms of measurement reproducibility and spatial variability.
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:46 -
Histological Validation of measurement of diffuse interstitial myocardial fibrosis by myocardial extravascular volume fraction from Modified Look-Locker imaging (MOLLI) T1 mapping at 3 T
Gadolinium (Gd) Extracellular volume fraction (ECV) by Cardiovascular Magnetic Resonance (CMR) has been proposed as a non-invasive method for assessment of diffuse myocardial fibrosis. Yet only few studies use...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:48 -
Single breath-hold 3D measurement of left atrial volume using compressed sensing cardiovascular magnetic resonance and a non-model-based reconstruction approach
Left atrial (LA) dilatation is associated with a large variety of cardiac diseases. Current cardiovascular magnetic resonance (CMR) strategies to measure LA volumes are based on multi-breath-hold multi-slice a...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:47 -
Comparison of cardiovascular magnetic resonance characteristics and clinical consequences in children and adolescents with isolated left ventricular non-compaction with and without late gadolinium enhancement
Although cardiovascular magnetic resonance (CMR) is showing increasingly diagnostic potential in left ventricular non-compaction (LVNC), relatively little research relevant to CMR is conducted in children with...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:44 -
Time elapsed after contrast injection is crucial to determine infarct transmurality and myocardial functional recovery after an acute myocardial infarction
In acute myocardial infarction (MI), late Gadolinium enhancement (LGE) has been proposed to include the infarcted myocardium and area at risk. However, little information is available on the optimal timing aft...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:43 -
Erratum: Relationship between MRI derived right ventricular mass and left ventricular involvement in patients with anderson-fabry disease
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:42 -
Evaluation of 3D multi-contrast joint intra- and extracranial vessel wall cardiovascular magnetic resonance
Multi-contrast vessel wall cardiovascular magnetic resonance (CMR) has demonstrated its capability for atherosclerotic plaque morphology measurement and component characterization in different vasculatures. Ho...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:41 -
Use of a 1.0 Tesla open scanner for evaluation of pediatric and congenital heart disease: a retrospective cohort study
Open cardiovascular magnetic resonance (CMR) scanners offer the potential for imaging patients with claustrophobia or large body size, but at a lower 1.0 Tesla magnetic field. This study aimed to evaluate the ...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:39 -
Characteristic cardiac phenotypes are detected by cardiovascular magnetic resonance in patients with different clinical phenotypes and genotypes of mitochondrial myopathy
Mitochondrial myopathies (MM) are a heterogeneous group of inherited conditions resulting from a primary defect in the mitochondrial respiratory chain with consecutively impaired cellular energy metabolism. Sm...
Citation: Journal of Cardiovascular Magnetic Resonance 2015 17:40